2-Amino-2'-O-methyladenosine

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For R&D use only.

Catalog NO.：A916798
CAS No. : 80791-87-3
Molecular Formula：C₁₁H₁₆N₆O₄
Molecular Weight： 296.28

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	80791-87-3	Appearance	White powder
Catalog Number	A916798	MDL Number	MFCD01630959
Molecular Formula	C₁₁H₁₆N₆O₄	Molecular Weight	296.28
Boiling Point	733.177°C at 760 mmHg	Melting Point	121-122°C
Flash Point	397.211°C	Density	1.983 g/cm3
Synonyms	(2R,3R,4R,5R)-5-(2,6-Diamino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302;H315;H320;H335	Class
Precautionary Statements	P261;P280;P301+P312;P302+P352;P305+P351+P338	Packing Group

Description

Tavaborole, also known as AN-2690 (trade name Kerydin) is a topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed. Tavaborole began its Phase 3 trials in December 2010 and was approved in July 2014. Tavaborole inhibits an essential fungal enzyme, Leucyl-tRNA synthetase, or LeuRS, required for protein synthesis. The inhibition of protein synthesis leads to termination of cell growth and cell death, eliminating the fungal infection. No treatment-related systemic side effects were observed in any of its clinical trials.

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