- Catalog NO.：A8996
- CAS No. : 669050-69-5
- Molecular Formula：C8H6N2O
- Molecular Weight： 146.15
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|Catalog Number||A8996||MDL Number||MFCD06738282|
|Molecular Formula||C8H6N2O||Molecular Weight||146.15|
|Boiling Point||358.3℃ at 760 mmHg||Melting Point||181-185℃|
|Storage Condition||Store in a tightly closed container,in a cool and dry place|
|Signal Word||Warning||UN Number|
|Precautionary Statements||P261-P280-P305+P351+P338||Packing Group|
Talabostat, also known as PT-100, is dipeptidyl peptidase inhibitor with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines.