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  • Catalog NO.:A845205
  • CAS No. : 951-77-9
  • Molecular Formula:C9H13N3O4
  • Molecular Weight: 227.22
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Product Details

CAS Number 951-77-9 Appearance White powder
Catalog Number A845205 MDL Number MFCD00006547
Molecular Formula C9H13N3O4 Molecular Weight 227.22
Boiling Point Melting Point
Flash Point Density
Synonyms 4-amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
Storage Condition Store in a tightly closed container,in a cool and dry place


GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302 Class
Precautionary Statements P280;P305+P351+P338 Packing Group


Nutlin-3b is less potent (+)-enantiomer of Nutlin-3 as p53 MDM2 inhibitor in comparison with more potent opposite (-)-enantiomer Nutlin-3a. Nutlin-3b may be used as negative control for non-MDM2 cellular activities. Potency of Nutlin-3b is much lower in the wild type p53 cells and has no effect regardless of the status of p53 cells.

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