1,2-Dipalmitoyl-sn-glycero-3-PS (sodium salt)

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For R&D use only.

Catalog NO.：A947599
CAS No. : 145849-32-7
Molecular Formula：C₃₈H₇₃NNaO₁₀P
Molecular Weight： 757.95

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Product Details

CAS Number	145849-32-7	Appearance
Catalog Number	A947599	MDL Number
Molecular Formula	C₃₈H₇₃NNaO₁₀P	Molecular Weight	757.95
Boiling Point		Melting Point
Flash Point		Density
Synonyms	(2S)-2-Amino-3-((((R)-2,3-bis(palmitoyloxy)propoxy)(hydroxy)phosphoryl)oxy)propanoic acid monosodium salt
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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