For R&D use only.


  • Catalog NO.:A950857
  • CAS No. : 1597402-27-1
  • Molecular Formula:C23H20Cl3N3O4
  • Molecular Weight: 508.78
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Product Details

CAS Number 1597402-27-1 Appearance
Catalog Number A950857 MDL Number MFCD11973900
Molecular Formula C23H20Cl3N3O4 Molecular Weight 508.78
Boiling Point Melting Point
Flash Point Density
Synonyms (S)-2-Amino-3-(4-((5-amino-2-phenylbenzo[d]oxazol-7-yl)methoxy)-3,5-dichlorophenyl)propanoic acid hydrochloride
Storage Condition Store in a tightly closed container,in a cool and dry place


GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302;H315;H319;H335 Class
Precautionary Statements P261;P305+P351+P338 Packing Group


  1. Elacridar, also known as GF120918A, is a P-glycoprotein (P-gp) inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. In vitro, GF120918A demonstrated high plasma protein binding across species, although a definitive protein binding evaluation was precluded by poor recovery, particularly in buffer and in mouse, rat, and dog plasma. GF120918A did not demonstrate potent inhibition of several human cytochrome P450 enzymes evaluated in vitro, with IC(50) values well above concentrations anticipated to be achieved in vivo. Together, these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects.

143851-98-3 (Elacridar HCl)

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(S)-2-Amino-3-(4-((5-amino-2-phenylbenzo[d]oxazol-7-yl)methoxy)-3,5-dichlorophenyl)propanoic acid hydrochloride