ML167
- N ° de catalogue:A889006
- N ° CAS. : 1285702-20-6
- Formule moléculaire:C19H17N3O3
- Masse moléculaire: 335.36
Remarque*
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Enquête en vrac
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Contrôle de qualité&SDS
détails du produit
Numero CAS | 1285702-20-6 | Apparence | |
Numéro de catalogue | A889006 | Numéro MDL | |
Formule moléculaire | C19H17N3O3 | Masse moléculaire | 335.36 |
Point d'ébullition | Point de fusion | ||
Point de rupture | Densité | ||
Synonymes | CID-44968231; NCGC00188654;(5-(4-(((5-methylfuran-2-yl)methyl)amino)quinazolin-6-yl)furan-2-yl)methanol | ||
Condition de stockage | Store in a tightly closed container,in a cool and dry place |
sécurité
Pictogramme SGH | |||
Mot de signal | Warning | Numéro UN | |
Mentions de danger | H302 | Classe | |
Conseils de prudence | P280-P305+P351+P338 | Groupe d'emballage |
La description
ML167 is the first highly selective inhibitor of of Cdc2-like kinase 4 (Clk4) with an IC50 of 136 nM for Clk4. The Cdc2-like kinases (ClkÂ’s) and the dual-specificity tyrosine phosphorylation-regulated kinases (DyrkÂ’s) have specified roles in gene splicing. Specifically, the Clk class of enzymes has been shown to phosphorylate the serine- and arginine-rich (SR) proteins, which are a major component of the spliceosome. |