Lasmiditan HCl
- N ° de catalogue：A904113
- N ° CAS. : 613677-28-4
- Formule moléculaire：C19H19ClF3N3O2
- Masse moléculaire： 413.83
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détails du produit
| Numero CAS | 613677-28-4 | Apparence | |
| Numéro de catalogue | A904113 | Numéro MDL | |
| Formule moléculaire | C19H19ClF3N3O2 | Masse moléculaire | 413.83 |
| Point d'ébullition | Point de fusion | ||
| Point de rupture | Densité | ||
| Synonymes | 2,4,6-Trifluoro-N-(6-((1-methylpiperidine-4-yl)carbonyl)pyridin-2-yl)benzamide HCl | ||
| Condition de stockage | Store in a tightly closed container,in a cool and dry place | ||
sécurité
| Pictogramme SGH |
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| Mot de signal | Warning | Numéro UN | |
| Mentions de danger | Classe | ||
| Conseils de prudence | Groupe d'emballage | ||
La description
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Lasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study. Lasmiditan showed efficacy in its primary endpoint, with a 2-hour placebo-subtracted headache response of 28.8%, though with frequent reports of dizziness, paresthesias, and vertigo. |
