Elafibranor (GFT505)
- Katalog-Nr.:A856857
- CAS-Nr. : 923978-27-2
- Molekularformel:C22H24O4S
- Molekulargewicht: 384.49
Hinweis*
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Massenanfrage
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Produktdetails
CAS-Nummer | 923978-27-2 | Aussehen | Yellow crystalline solid |
Katalognummer | A856857 | MDL-Nummer | MFCD27987940 |
Molekularformel | C22H24O4S | Molekulargewicht | 384.49 |
Siedepunkt | 569.0±50.0°C at 760 mmHg | Schmelzpunkt | |
Flammpunkt | Dichte | ||
Synonyme | (E)-2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxoprop-1-en-1-yl)phenoxy)-2-methylpropanoic acid | ||
Lagerungszustand | Store in a tightly closed container,in a cool and dry place |
Sicherheit
GHS-Piktogramm | |||
Signalwort | Warning | UN-Nummer | |
Gefahrenhinweise | H302-H315-H319-H335 | Klasse | |
Sicherheitshinweise | P261-P305+P351+P338 | Verpackungsgruppe |
Beschreibung
CZC24832 is the first selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in vitro and in vivo models of inflammation. Extensive target- and cell-based profiling of CZC24832 revealed regulation of interleukin-17-producing T helper cell (T(H)17) differentiation by PI3Kγ, thus reinforcing selective inhibition of PI3Kγ as a potential treatment for inflammatory and autoimmune diseases. |