AG14361
- Katalog-Nr.:A854353
- CAS-Nr. : 328543-09-5
- Molekularformel:C19H20N4O
- Molekulargewicht: 320.39
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Qualitätskontrolle&SDS
Produktdetails
CAS-Nummer | 328543-09-5 | Aussehen | |
Katalognummer | A854353 | MDL-Nummer | |
Molekularformel | C19H20N4O | Molekulargewicht | 320.39 |
Siedepunkt | Schmelzpunkt | ||
Flammpunkt | Dichte | ||
Synonyme | 1-(4-((dimethylamino)methyl)phenyl)-8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one;2-[4-[(Dimethylamino)methyl]phenyl]-5,6-dihydroimidazo[4,5,1-jk][1,4]benzodiazepin-7(4H)-one;AG-14361 | ||
Lagerungszustand | Store in a tightly closed container,in a cool and dry place |
Sicherheit
GHS-Piktogramm | |||
Signalwort | Warning | UN-Nummer | |
Gefahrenhinweise | H302-H315-H319-H335 | Klasse | |
Sicherheitshinweise | P261-P305+P351+P338 | Verpackungsgruppe |
Beschreibung
AG14361 is a PARP-1 inhibitor with Ki < 5 nmol/L. AG14361 is at least 1000-fold more potent than the benzamides. The IC50 for AG14361 is 29 nM in permeabilized SW620 cells and 14 nM in intact SW620 cells. |