Maraviroc
- Catalog NO.:A823806
- CAS No. : 376348-65-1
- Molecular Formula:C29H41F2N5O
- Molecular Weight: 513.67
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2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 376348-65-1 | Appearance | |
Catalog Number | A823806 | MDL Number | MFCD13188530 |
Molecular Formula | C29H41F2N5O | Molecular Weight | 513.67 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | Maraviroc; Selzentry; Celsentri; UK-427857;4,4-difluoro-N-[(1R)-3-[(1S,5R)-3-(3-isopropyl-5-methyl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenyl-propyl]cyclohexanecarboxamide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram |
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Signal Word | Warning | UN Number | |
Hazard Statements | H302 | Class | |
Precautionary Statements | P280-P305+P351+P338 | Packing Group |
Description
Maraviroc is an antiviral, potent, non-competitive CKR-5 receptor antagonist that inhibits binding of HIV viral coat protein gp120. Maraviroc inhibits MIP-1β-stimulated γ-S-GTP binding to HEK-293 cell membranes, indicating its ability to inhibit chemokine-dependent stimulation of GDP-GTP exchange at the CKR-5/G protein complex. Maraviroc also inhibits the downstream event of chemokine-induced intracellular calcium redistribution. |