ATB-346
- Catalog NO.:A891048
- CAS No. : 1226895-20-0
- Molecular Formula:C21H19NO3S
- Molecular Weight: 365.45
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Product Details
CAS Number | 1226895-20-0 | Appearance | |
Catalog Number | A891048 | MDL Number | MFCD19443776 |
Molecular Formula | C21H19NO3S | Molecular Weight | 365.45 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 4-carbamothioylphenyl 2-(6-methoxynaphthalen-2-yl)propanoate | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram |
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Signal Word | Warning | UN Number | |
Hazard Statements | H302 | Class | |
Precautionary Statements | P264-P270-P301+P312-P330 | Packing Group |
Description
ATB-346 is anti- inflammatory agent, which is structurally an analogue of naproxen. ABT-346 exhibits anti-inflammatory properties similar to naproxen, but with substantially reduced gastrointestinal toxicity. ATB-346 suppressed colonic prostaglandin synthesis and whole blood thromboxane synthesis as effectively as naproxen, but did not induce any gastrointestinal injury. ATB-346 exerts superior chemopreventive effects to those of naproxen, while sparing the gastrointestinal tract of the injury normally associated with use of the parent drug. ATB-346 may therefore be an attractive agent for chemoprevention of colon cancer, and possibly of cancers in other tissues. |