LY2801653 HCl
- Catalog NO.:A904120
- CAS No. : 1206801-37-7
- Molecular Formula:C30H24Cl2F2N6O3
- Molecular Weight: 625.45
1. Please click the
![](/usr/uploads/3/201903/xunpan.png.png)
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 1206801-37-7 | Appearance | |
Catalog Number | A904120 | MDL Number | |
Molecular Formula | C30H24Cl2F2N6O3 | Molecular Weight | 625.45 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | Merestinib HCl;N-(3-fluoro-4-((1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl)oxy)phenyl)-1-(4-fluorophenyl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide HCl;LY2801653 dihydrochloride | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram |
![]() |
||
Signal Word | Warning | UN Number | |
Hazard Statements | Class | ||
Precautionary Statements | Packing Group |
Description
Merestinib, also known as LY2801653, is a n orally available, small molecule inhibitor of the proto-oncogene c-Met (mesenchymal-epithelial transition, also known as hepatocyte growth factor receptor [HGFR]) with potential antineoplastic activity. c-Met inhibitor LY2801653 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing constitutively activated c-Met protein. This agent has potent anti-tumor efficacy in mono- and combination therapy in a broad range of cancers. |