Binimetinib
- Catalog NO.:A857417
- CAS No. : 606143-89-9
- Molecular Formula:C17H15BrF2N4O3
- Molecular Weight: 441.23
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 606143-89-9 | Appearance | White powder |
Catalog Number | A857417 | MDL Number | MFCD22124525 |
Molecular Formula | C17H15BrF2N4O3 | Molecular Weight | 441.23 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | MEK 162; ARRY162;5-[(4-Bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide;ARRY-162 | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
Binimetinib, also known as MEK162 (ARRY-162), is an oral, highly selective MEK inhibitor. In preclinical studies, MEK162 showed significant antitumor activities in cell lines and animal models. MEK162 is the first targeted therapy to show activity in patients with NRAS -mutated melanoma and might offer a new option for a cancer with few effective treatments. |