BML 190
- Catalog NO.:A846165
- CAS No. : 2854-32-2
- Molecular Formula:C23H23ClN2O4
- Molecular Weight: 426.897
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 2854-32-2 | Appearance | |
Catalog Number | A846165 | MDL Number | MFCD01317813 |
Molecular Formula | C23H23ClN2O4 | Molecular Weight | 426.897 |
Boiling Point | 586.7±50.0°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | LM 4131; IMMA;1-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)-2-morpholinoethanone;2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl)-ethanone | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
BML-190, also known as IMMA and LM-4131 or Indomethacin Morpholinylamide, is selective CB2 receptor agonist. The binding constant for the CB2 receptor is 435 nM compared to >20,000 nM for the cannabinoid receptor, CB1. BML-190 reduces the basal levels of inositol phosphate production in cells expressing the CB(2) receptor and 16z44. BML-190 acts as inverse agonist at the human CB(2) receptor acting via G alpha(i/o) and G alpha(q) family-coupled pathways. |