Fabomotizole Hydrochloride
- Catalog NO.:A881777
- CAS No. : 173352-21-1
- Molecular Formula:C15H22ClN3O2S
- Molecular Weight: 343.87
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Product Details
CAS Number | 173352-21-1 | Appearance | White powder |
Catalog Number | A881777 | MDL Number | MFCD01413136 |
Molecular Formula | C15H22ClN3O2S | Molecular Weight | 343.87 |
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Synonyms | 4-(2-((5-ethoxy-1H-benzo[d]imidazol-2-yl)thio)ethyl)morpholine hydrochloride | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
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Precautionary Statements | Packing Group |
Description
Afobazole, also known as Fabomotizole, Obenoxazine and CM346, is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Fabomotizole has found little clinical use outside Russia and has not been evaluated by the FDA. |