Pictilisib mesylate
- Catalog NO.:A858922
- CAS No. : 957054-33-0
- Molecular Formula:C25H35N7O9S4
- Molecular Weight: 705.85
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Product Details
CAS Number | 957054-33-0 | Appearance | |
Catalog Number | A858922 | MDL Number | |
Molecular Formula | C25H35N7O9S4 | Molecular Weight | 705.85 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 4-(2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine dimesylate;GDC-0941 dimethanesulfonate | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | Class | ||
Precautionary Statements | Packing Group |
Description
Pictilisib, also known as Pictrelisib, GDC-0941, RG7321 and GNE0941 , is an orally bioavailable, and is a potent small-molecule thieno[3,2-d]pyrimidine inhibitor of the class I phosphatidylinositol 3 kinase (PI3K) isoforms p100alpha and p100delta with potential antineoplastic activity. PI3K inhibitor GDC-0941 selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway; inhibition of tumor cell growth, motility and survival in susceptible tumor cell populations may result. |