AGI-6780
- Catalog NO.:A854357
- CAS No. : 1432660-47-3
- Molecular Formula:C21H18F3N3O3S2
- Molecular Weight: 481.51
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 1432660-47-3 | Appearance | Off-white powder |
Catalog Number | A854357 | MDL Number | MFCD26097285 |
Molecular Formula | C21H18F3N3O3S2 | Molecular Weight | 481.51 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | N-Cyclopropyl-4-(3-thienyl)-3-[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-benzenesulfonamide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
AGI-6780 is a potent and selective IDH2 inhibitor. AGI-6780 inhibits the tumor-associated mutant IDH2/R140Q. Treatment with AGI-6780 induced differentiation of TF-1 erythroleukemia and primary human acute myelogenous leukemia cells in vitro. Inhibitors targeting mutant IDH2/R140Q could have potential applications as a differentiation therapy for cancer. |