FR180204
- Catalog NO.:A863140
- CAS No. : 865362-74-9
- Molecular Formula:C18H13N7
- Molecular Weight: 327.34
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 865362-74-9 | Appearance | Yellow powder |
Catalog Number | A863140 | MDL Number | MFCD14585805 |
Molecular Formula | C18H13N7 | Molecular Weight | 327.34 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1h-pyrazolo[3,4-c]pyridazin-3-amine;FR 180204 | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302 | Class | |
Precautionary Statements | P264-P270-P301+P312-P330-P501 | Packing Group |
Description
Selective ERK inhibitor (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Displays 30-fold selectivity for ERK over p38α (IC50 = 10 μM); displays no activity against human recombinant MEK1, MKK4, IKKα, PKCα, Src, Syc and PDGFα at concentrations less than 30 μM. Also inhibits TGFβ-induced AP-1 activation in Mv1Lu cells (IC50 = 3.1 μM). |