Saracatinib
- Catalog NO.:A823939
- CAS No. : 379231-04-6
- Molecular Formula:C27H32ClN5O5
- Molecular Weight: 542.03
Note*
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3. The price does not include shipping and bank charges.
Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 379231-04-6 | Appearance | White powder |
Catalog Number | A823939 | MDL Number | MFCD09832698 |
Molecular Formula | C27H32ClN5O5 | Molecular Weight | 542.03 |
Boiling Point | 671.25°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | AZD-0530;N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-tetrahydropyran-4-yloxy-quinazolin-4-amine | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
Saracatinib, also known as AZD0530, is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities. Src and Abl are protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. Saracatinib binds to and inhibits these tyrosine kinases and their effects on cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival. |