Mocetinostat
- N ° de catalogue：A846294
- N ° CAS. : 726169-73-9
- Formule moléculaire：C23H20N6O
- Masse moléculaire： 396.45
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détails du produit
| Numero CAS | 726169-73-9 | Apparence | White to off-white solid |
| Numéro de catalogue | A846294 | Numéro MDL | MFCD10565970 |
| Formule moléculaire | C23H20N6O | Masse moléculaire | 396.45 |
| Point d'ébullition | Point de fusion | ||
| Point de rupture | Densité | ||
| Synonymes | N-(2-Aminophenyl)-4-([[4-(pyridin-3-yl)pyrimidin-2-yl]amino]methyl)benzamide | ||
| Condition de stockage | Store in a tightly closed container,in a cool and dry place | ||
sécurité
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| Mot de signal | Warning | Numéro UN | |
| Mentions de danger | H302-H315-H319-H335 | Classe | |
| Conseils de prudence | P261-P305+P351+P338 | Groupe d'emballage | |
La description
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Mocetinostat, also known as MGCD-0103, is a rationally designed, orally available, Class 1-selective, small molecule, 2-aminobenzamide HDAC inhibitor with potential antineoplastic activity. Mocetinostat binds to and inhibits Class 1 isoforms of HDAC, specifically HDAC 1, 2 and 3, which may result in epigenetic changes in tumor cells and so tumor cell death; although the exact mechanism has yet to be defined, tumor cell death may occur through the induction of apoptosis, differentiation, cell cycle arrest, inhibition of DNA repair, upregulation of tumor suppressors, down regulation of growth factors, oxidative stress, and autophagy, among others. |
