3-Cyclopentyl-3-(((9H-fluoren-9-yl)methoxy)carbonyl)amino-propionic acid
- Catalog NO.:A933956
- CAS No. : 954225-72-0
- Molecular Formula:C23H25NO4
- Molecular Weight: 379.45
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Product Details
CAS Number | 954225-72-0 | Appearance | |
Catalog Number | A933956 | MDL Number | |
Molecular Formula | C23H25NO4 | Molecular Weight | 379.45 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 3-Cyclopentyl-3-(((9H-fluoren-9-yl)methoxy)carbonyl)amino-propionic acid | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram |
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Signal Word | Warning | UN Number | |
Hazard Statements | Class | ||
Precautionary Statements | Packing Group |
Description
Talabostat, also known as PT-100, is dipeptidyl peptidase inhibitor with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines. |