For R&D use only.

5-Chloropyridazine-3-carboxylic acid

  • Catalog NO.:A926283
  • CAS No. : 1211587-01-7
  • Molecular Formula:C5H3ClN2O2
  • Molecular Weight: 158.54
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Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 1211587-01-7 Appearance Light yellow powder
Catalog Number A926283 MDL Number MFCD20659173
Molecular Formula C5H3ClN2O2 Molecular Weight 158.54
Boiling Point 420.3±25.0°C at 760 mmHg Melting Point
Flash Point Density
Synonyms 5-Chloropyridazine-3-carboxylic acid
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group

Description

Alpelisib, also known as BLY719, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BYL719 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis. Dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents. Check for active clinical trials or closed clinical trials using this agent.

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5-Chloropyridazine-3-carboxylic acid
5-Chloropyridazine-3-carboxylic acid