- Catalog NO.：A946588
- CAS No. : 1262770-73-9
- Molecular Formula：C18H21N5S
- Molecular Weight： 339.46
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|CAS Number||1262770-73-9||Appearance||Off-white powder|
|Catalog Number||A946588||MDL Number|
|Molecular Formula||C18H21N5S||Molecular Weight||339.46|
|Boiling Point||Melting Point|
|Storage Condition||Store in a tightly closed container,in a cool and dry place|
|Signal Word||Warming||UN Number|
|Precautionary Statements||P261;P305+P351+P338||Packing Group|
Tavaborole, also known as AN-2690 (trade name Kerydin) is a topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed. Tavaborole began its Phase 3 trials in December 2010 and was approved in July 2014. Tavaborole inhibits an essential fungal enzyme, Leucyl-tRNA synthetase, or LeuRS, required for protein synthesis. The inhibition of protein synthesis leads to termination of cell growth and cell death, eliminating the fungal infection. No treatment-related systemic side effects were observed in any of its clinical trials.