BI-D1870

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Pour R&D utiliser seulement.

N ° de catalogue：A871649
N ° CAS. : 501437-28-1
Formule moléculaire：C₁₉H₂₃F₂N₅O₂
Masse moléculaire： 391.42

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détails du produit

Numero CAS	501437-28-1	Apparence	Off-White powder
Numéro de catalogue	A871649	Numéro MDL	MFCD11223662
Formule moléculaire	C₁₉H₂₃F₂N₅O₂	Masse moléculaire	391.42
Point d'ébullition	579.3°C at 760 mmHg	Point de fusion
Point de rupture		Densité
Synonymes	2-((3,5-Difluoro-4-hydroxyphenyl)amino)-8-isopentyl-5,7-dimethyl-7,8-dihydropteridin-6(5H)-one
Condition de stockage	Store in a tightly closed container,in a cool and dry place

sécurité

Pictogramme SGH
Mot de signal	Warning	Numéro UN
Mentions de danger	H302-H315-H319-H335	Classe
Conseils de prudence	P261-P305+P351+P338	Groupe d'emballage

La description

FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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Mes pistes: Benzyl ((1H-tetrazol-5-yl)methyl)carbamate 2-Nitro-4-(trifluoromethoxy)benzoic acid (R)-1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethylamine XL388

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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
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H318	Serious eye damage/eye irritation (Category 1)
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H330	Acute toxicity,inhalation (Category 1, 2)
H331	Acute toxicity,inhalation (Category 3)
H332	Acute toxicity,inhalation (Category 4)
H333	Acute toxicity,inhalation (Category 5)
H334	Sensitisation, respiratory (Category 1)
H335	Specific target organ toxicity, single exposure; Respiratory tract irritation (Category 3)
H336	Specific target organ toxicity,single exposure; Narcoticeffects (Category 3)
H340	Germ cell mutagenicity (Category 1A, 1B)
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