Elafibranor (GFT505)

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Pour R&D utiliser seulement.

N ° de catalogue：A856857
N ° CAS. : 923978-27-2
Formule moléculaire：C₂₂H₂₄O₄S
Masse moléculaire： 384.49

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détails du produit

Numero CAS	923978-27-2	Apparence	Yellow crystalline solid
Numéro de catalogue	A856857	Numéro MDL	MFCD27987940
Formule moléculaire	C₂₂H₂₄O₄S	Masse moléculaire	384.49
Point d'ébullition	569.0±50.0°C at 760 mmHg	Point de fusion
Point de rupture		Densité
Synonymes	(E)-2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxoprop-1-en-1-yl)phenoxy)-2-methylpropanoic acid
Condition de stockage	Store in a tightly closed container,in a cool and dry place

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La description

CZC24832 is the first selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in vitro and in vivo models of inflammation. Extensive target- and cell-based profiling of CZC24832 revealed regulation of interleukin-17-producing T helper cell (T(H)17) differentiation by PI3Kγ, thus reinforcing selective inhibition of PI3Kγ as a potential treatment for inflammatory and autoimmune diseases.

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